Bioreactors for Extracorporeal Liver Support
نویسندگان
چکیده
منابع مشابه
Current development of bioreactors for extracorporeal bioartificial liver (Review).
The research and development of extracorporeal bioartificial liver is gaining pace in recent years with the introduction of a myriad of optimally designed bioreactors with the ability to maintain long-term viability and liver-specific functions of hepatocytes. The design considerations for bioartificial liver are not trivial; it needs to consider factors such as the types of cell to be cultured...
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Given that liver failure continues to pose an enormous clinical challenge, the concept of hepatic dialysis has enjoyed significant interest. In particular, many investigations have examined the therapeutic mechanisms and efficacy of artificial albumin dialysis based systems in acute on chronic liver failure, the results of which have been conflicting. Albumin dialysis systems do not appear to s...
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A cute liver failure (ALF) patients have a high risk of mortality. The elective treatment for ALF still is orthotopic liver transplantation. Donor organ scarcity and the associated high costs make transplantation possible for only about one third of the patients on the transplantation waiting list. Engineering a biological liver substitute is an interesting alternative to the traditional ALF th...
متن کاملRecent Advances in Clinical Practice Prospects for Extracorporeal Liver Support
Correspondence to: Dr R Jalan, Liver Failure Group, Institute of Hepatology, University College London Medical School and University College London Hospitals, 69-75 Chenies Mews, London WC1E 6HX, UK; [email protected] _________________________ T his present review is timely with the increasing use of the molecular adsorbents recirculating system (MARS) for the management of liver failure, with ...
متن کاملan evaluation of the usefulness of extracorporeal liver support techniques in patients hospitalized in the icu for severe liver dysfunction secondary to alcoholic liver disease
objectives the main aim of this study was to evaluate the usefulness of applying extracorporeal liver support techniques to treat this group of patients. patients and methods the data from 23 hospital admissions of 21 patients with ald who were admitted to the department of anesthesiology and intensive therapy (a⁢) at the dr wł. biegański regional specialist hospital in łódź between march 20...
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ژورنال
عنوان ژورنال: Cell Transplantation
سال: 2006
ISSN: 0963-6897,1555-3892
DOI: 10.3727/000000006783982296